SARS CoV-2 Full Length Spike Protein mRNA
CATALOG#
SPIKE100U: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE500U: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE1000U: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE100P: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE500P: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE1000P: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE100M: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
SPIKE500M: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
SPIKE1000M: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
Also available as mRNA-LNP
(To pay with a purchase order, please send your purchase order to sales@messenger.bio)
Messenger Bio's SARS CoV-2 Full Length Spike Protein mRNA is engineered to highly express the same spike protein as common mRNA vaccines against COVID-19.
We developed this mRNA by fine-tuning the key determinants of SARS CoV-2 full length spike protein mRNA expression, including the 5’ and 3’ UTRs as well as the protein-coding region itself.
Our Full Length Spike mRNA includes a Cap1 structure (biologically superior to Cap0), a highly expressing 5’ UTR and highly stable 3’ UTR, a 100-nt poly(A) tail, and a codon-optimized open reading frame. Choose from unmodified or modified (N1-methylpseudouridine or 5-methoxyuridine) bases. Both types of modified bases have been shown to enhance protein expression in vitro and in vivo.
Our robust purification process removes dsRNA contaminants and other reaction components, generating highly pure mRNA that is capable of inducing very high levels of protein expression in diverse cell types, while causing minimal cellular innate immune activation (virtually undetectable).
As with all our mRNAs, this Full Length Spike mRNA comes ready-to-use in a 1 mM sodium citrate buffer (pH 6.5), which is ideal for preserving RNA stability and extending shelf-life. Just complex with your favorite transfection reagent, and you’re ready to go. Alternatively, speak to us about our ready-to-transfect LNP formulations.
If you would like to request a different amount of mRNA than what is listed on our website, or a different type of modified base, or any more information about our Full Length Spike mRNA, send us an email at hello@messenger.bio and we’ll be happy to help.
For Research Use Only. See Terms of Sale for more.
CATALOG#
SPIKE100U: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE500U: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE1000U: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE100P: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE500P: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE1000P: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE100M: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
SPIKE500M: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
SPIKE1000M: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
Also available as mRNA-LNP
(To pay with a purchase order, please send your purchase order to sales@messenger.bio)
Messenger Bio's SARS CoV-2 Full Length Spike Protein mRNA is engineered to highly express the same spike protein as common mRNA vaccines against COVID-19.
We developed this mRNA by fine-tuning the key determinants of SARS CoV-2 full length spike protein mRNA expression, including the 5’ and 3’ UTRs as well as the protein-coding region itself.
Our Full Length Spike mRNA includes a Cap1 structure (biologically superior to Cap0), a highly expressing 5’ UTR and highly stable 3’ UTR, a 100-nt poly(A) tail, and a codon-optimized open reading frame. Choose from unmodified or modified (N1-methylpseudouridine or 5-methoxyuridine) bases. Both types of modified bases have been shown to enhance protein expression in vitro and in vivo.
Our robust purification process removes dsRNA contaminants and other reaction components, generating highly pure mRNA that is capable of inducing very high levels of protein expression in diverse cell types, while causing minimal cellular innate immune activation (virtually undetectable).
As with all our mRNAs, this Full Length Spike mRNA comes ready-to-use in a 1 mM sodium citrate buffer (pH 6.5), which is ideal for preserving RNA stability and extending shelf-life. Just complex with your favorite transfection reagent, and you’re ready to go. Alternatively, speak to us about our ready-to-transfect LNP formulations.
If you would like to request a different amount of mRNA than what is listed on our website, or a different type of modified base, or any more information about our Full Length Spike mRNA, send us an email at hello@messenger.bio and we’ll be happy to help.
For Research Use Only. See Terms of Sale for more.
CATALOG#
SPIKE100U: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE500U: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE1000U: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (unmodified)
SPIKE100P: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE500P: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE1000P: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (N1-methylpseudouridine)
SPIKE100M: 100 µg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
SPIKE500M: 500 µg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
SPIKE1000M: 1 mg SARS CoV-2 Full Length Spike Protein mRNA (5-methoxyuridine)
Also available as mRNA-LNP
(To pay with a purchase order, please send your purchase order to sales@messenger.bio)
Messenger Bio's SARS CoV-2 Full Length Spike Protein mRNA is engineered to highly express the same spike protein as common mRNA vaccines against COVID-19.
We developed this mRNA by fine-tuning the key determinants of SARS CoV-2 full length spike protein mRNA expression, including the 5’ and 3’ UTRs as well as the protein-coding region itself.
Our Full Length Spike mRNA includes a Cap1 structure (biologically superior to Cap0), a highly expressing 5’ UTR and highly stable 3’ UTR, a 100-nt poly(A) tail, and a codon-optimized open reading frame. Choose from unmodified or modified (N1-methylpseudouridine or 5-methoxyuridine) bases. Both types of modified bases have been shown to enhance protein expression in vitro and in vivo.
Our robust purification process removes dsRNA contaminants and other reaction components, generating highly pure mRNA that is capable of inducing very high levels of protein expression in diverse cell types, while causing minimal cellular innate immune activation (virtually undetectable).
As with all our mRNAs, this Full Length Spike mRNA comes ready-to-use in a 1 mM sodium citrate buffer (pH 6.5), which is ideal for preserving RNA stability and extending shelf-life. Just complex with your favorite transfection reagent, and you’re ready to go. Alternatively, speak to us about our ready-to-transfect LNP formulations.
If you would like to request a different amount of mRNA than what is listed on our website, or a different type of modified base, or any more information about our Full Length Spike mRNA, send us an email at hello@messenger.bio and we’ll be happy to help.
For Research Use Only. See Terms of Sale for more.
